Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 7/20 | 0.56 |
| ▸ | PNP | P00491 | 4/20 | 0.47 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HINT1 | P49773 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663828 | 0.89 | HPRT1 (0.70) | HPRT1PNPNT5EPOLBADORA3 | |
| SCHEMBL8666797 | 0.86 | HPRT1 (0.52) | HPRT1PNPFUT5NT5EPOLB | |
| SCHEMBL8663380 | 0.82 | AHCY (0.51) | NT5E | |
| SCHEMBL8661786 | 0.82 | AHCY (0.51) | NT5E | |
| SCHEMBL12154574 | 0.79 | HPRT1 (0.51) | HPRT1PNPFUT5NT5EPOLB | |
| SCHEMBL12154654 | 0.79 | NT5E (0.51) | HPRT1PNPFUT5NT5EPOLB | |
| SCHEMBL12300885 | 0.79 | NT5E (0.51) | HPRT1PNPFUT5NT5EPOLB | |
| SCHEMBL12154637 | 0.78 | HPRT1 (0.47) | HPRT1PNPFUT5NT5EPOLB | |
| SCHEMBL8663157 | 0.78 | HPRT1 (0.49) | HPRT1PNPNT5EPOLBADORA3 | |
| SCHEMBL8662662 | 0.78 | HPRT1 (0.49) | HPRT1PNPNT5EPOLBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744600-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-04-28 | — | — | US | disclosed |