SCHEMBL8663380

SCHEMBL8663380

CCOP(=O)(COC1CC(n2cnc3c(N)ncnc32)C(F)C1O)OCC

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
AHCY P23526 14/20 0.51
ADORA2B P29275 1/20 0.49
RNASEL Q05823 1/20 0.46
NT5E P21589 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8661786 1.00 AHCY (0.51) AHCYADORA2BRNASELNT5E
SCHEMBL8661479 0.88 AHCY (0.52) AHCYADORA2BRNASELNT5E
SCHEMBL8665069 0.88 AHCY (0.52) AHCYADORA2BRNASELNT5E
SCHEMBL8662391 0.85 AHCY (0.47) AHCYADORA2B
SCHEMBL8663734 0.85 AHCY (0.47) AHCYADORA2B
SCHEMBL8662018 0.82 HPRT1 (0.56) NT5E
SCHEMBL15948858 0.81 ADCY5 (0.56) AHCYADORA2B
SCHEMBL8660803 0.79 ADCY5 (0.65) ADORA2B
SCHEMBL8661785 0.76 ADCY5 (0.64)
SCHEMBL8661134 0.76 ADCY5 (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744600-A VIRICIDES, ANTITUMOR AGENTS INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1998-04-28 US disclosed