Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 10/20 | 0.52 |
| ▸ | PNP | P00491 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665197 | 0.87 | HPRT1 (0.68) | HPRT1PNPNT5E | |
| SCHEMBL8662018 | 0.86 | HPRT1 (0.56) | HPRT1PNPPOLBNT5EFUT5 | |
| SCHEMBL8663734 | 0.81 | AHCY (0.47) | — | |
| SCHEMBL8662391 | 0.81 | AHCY (0.47) | — | |
| SCHEMBL8663157 | 0.81 | HPRT1 (0.49) | HPRT1PNPPOLBMEN1KMT2A | |
| SCHEMBL8662662 | 0.81 | HPRT1 (0.49) | HPRT1PNPPOLBMEN1KMT2A | |
| SCHEMBL13531167 | 0.78 | HPRT1 (0.48) | HPRT1PNPPOLBMEN1KMT2A | |
| SCHEMBL12300885 | 0.78 | NT5E (0.51) | HPRT1PNPPOLBNT5EFUT5 | |
| SCHEMBL12154654 | 0.78 | NT5E (0.51) | HPRT1PNPPOLBNT5EFUT5 | |
| SCHEMBL12154637 | 0.77 | HPRT1 (0.47) | HPRT1PNPPOLBNT5EFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744600-A | VIRICIDES, ANTITUMOR AGENTS | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1998-04-28 | — | — | US | disclosed |