SCHEMBL8662033

SCHEMBL8662033

Cc1c(N)ccc([S+]([O-])c2ccc(N)c(C)c2C)c1C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.40
TSHR P16473 2/20 0.40
PIK3CA P42336 1/20 0.40
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.32
TP53 P04637 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1287898 0.80 CYP3A4 (0.43) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL29384787 0.76 CYP3A4 (0.62) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL33944 0.76 CYP3A4 (0.62) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL3684645 0.75 CYP1A2 (0.31) TSHR
Hydrochloric Acid SCHEMBL529931 0.73 CYP3A4 (0.59) CYP3A4TSHRPIK3CAALDH1A1TDP1
Hydrochloric Acid SCHEMBL309540 0.73 CYP3A4 (0.59) CYP3A4TSHRPIK3CAALDH1A1TDP1
Hydrochloric Acid SCHEMBL29566187 0.73 CYP3A4 (0.59) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL9667 0.66 CYP3A4 (0.50) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL33509 0.66 CYP3A4 (0.50) CYP3A4TSHRPIK3CAALDH1A1TDP1
SCHEMBL2787911 0.64 ACHE (0.31) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed