Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA known ✓ | P42336 | 1/20 | 0.59 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.37 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL309540 | 1.00 | CYP3A4 (0.59) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL29566187 | 1.00 | CYP3A4 (0.59) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| SCHEMBL33944 | 0.96 | CYP3A4 (0.62) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| SCHEMBL29384787 | 0.96 | CYP3A4 (0.62) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL526310 | 0.87 | POLB (0.48) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL154618 | 0.87 | POLB (0.48) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL553599 | 0.87 | CYP3A4 (0.48) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL6369794 | 0.87 | POLB (0.48) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL3871332 | 0.85 | CYP3A4 (0.46) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| SCHEMBL9667 | 0.83 | CYP3A4 (0.50) | CYP3A4TSHRPIK3CAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940828-A | Method for determining total aldehydes in one or more of crude 2, 5-furandicarboxylic acid (FDCA), crude terephthalic acid (TPA), and esters thereof | 阿彻丹尼尔斯米德兰德公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116288732-A | Preparation method of DMPDPbI4 perovskite monocrystal with zirconium ion implantation and application of DMPDPbI4 perovskite monocrystal in photoelectric detector | 西北大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116121912-A | Preparation method of graphene oxide fiber | 浙江大学 | 2023-05-16 | — | — | CN | claimed |
| CN-115815883-A | Colorless and transparent flux for postweld residues and preparation method thereof | 云南锡业锡材有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115655837-A | Ammonium salt solution, ferric diamine-Alisine blue staining solution and application thereof | 河南赛诺特生物技术有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-111289503-B | Instrument and method for in-situ detection of deep-sea dissolved sulfide | 国家深海基地管理中心 | 2022-12-09 | — | — | CN | claimed |
| CN-112853409-B | Silver-containing plating solution and preparation method of foam metal material | 哈尔滨工业大学（深圳） | 2022-07-22 | — | — | CN | claimed |
| CN-114609060-A | Method for measuring sulfide in industrial wastewater | 陕西化工研究院有限公司 | 2022-06-10 | — | — | CN | claimed |
| CN-112853409-A | Silver-containing plating solution and preparation method of foam metal material | 哈尔滨工业大学（深圳） | 2021-05-28 | — | — | CN | claimed |
| CN-111289503-A | Instrument and method for in-situ detection of deep-sea dissolved sulfide | 国家深海基地管理中心 | 2020-06-16 | — | — | CN | claimed |
| US-20160229952-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | claimed |
| CN-104251858-A | In-vitro detection method used for detecting oxidative stress marker d-ROMs | WANG CHEN | 2014-12-31 | — | — | CN | claimed |
| CN-102565262-B | Determination method for hydrogen sulfide in mainstream smoke of cigarette | CHINA TOBACCO JIANGSU IND CO | 2014-01-22 | — | — | CN | claimed |
| US-20130184429-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | THE UNIVERSITY OF AKRON (US) | 2013-07-18 | — | — | US | claimed |
| EP-2598552-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | University Of Akron (US) | 2013-06-05 | — | — | EP | claimed |
| CN-102565262-A | Determination method for hydrogen sulfide in mainstream smoke of cigarette | CHINA TOBACCO JIANGSU IND CO | 2012-07-11 | — | — | CN | claimed |
| WO-2012015481-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | UNIVERSITY OF AKRON (US) | 2012-02-02 | — | — | WO | claimed |
| EP-0722710-B1 | Keratinous fiber oxidation dyeing composition and the dyeing process using this composition | OREAL (FR) | 1999-10-06 | — | — | EP | claimed |
| US-4108729-A | Paper booklet for presumptive diagnosis of Neisseria Gonorrhoeae in the male | U.S. PACKAGING CORP. (US) | 1978-08-22 | — | — | US | claimed |
| US-4018653-A | Instrument for the detection of Neisseria gonorrhoeae without culture | U.S. PACKAGING CORPORATION (US) | 1977-04-19 | — | — | US | claimed |