Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 16/20 | 0.36 |
| ▸ | PPARA | Q07869 | 14/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440670 | 0.87 | PPARG (0.46) | PPARGPPARACYP3A4CYP2C9KCNH2 | |
| SCHEMBL8662208 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TSHRPPARGPPARACYP3A4 | |
| SCHEMBL8662202 | 0.76 | PPARG (0.38) | ALDH1A1TSHRPPARGPPARACYP3A4 | |
| SCHEMBL8472017 | 0.71 | POLB (0.45) | POLBALDH1A1TSHRMAPTTHRB | |
| SCHEMBL8471742 | 0.71 | MAPT (0.41) | POLBALDH1A1KCNH2MAPTTHRB | |
| SCHEMBL8523889 | 0.70 | POLB (0.47) | POLBALDH1A1TSHRCYP3A4CYP2C9 | |
| SCHEMBL3774754 | 0.69 | MAPT (0.50) | POLBALDH1A1MAPTTHRB | |
| SCHEMBL8500896 | 0.69 | KDM4E (0.46) | POLBPPARGPPARACYP3A4CYP2C9 | |
| SCHEMBL6032173 | 0.68 | MAPT (0.54) | POLBALDH1A1MAPTTHRB | |
| SCHEMBL8659796 | 0.68 | MAPT (0.43) | POLBALDH1A1TSHRPPARGCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824694-A | Thiazolidine derivatives for the treatment of psoriasis | BETHESDA PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |