Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662192 | 0.82 | CYP3A4 (0.53) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL10813992 | 0.80 | OGG1 (0.54) | OGG1CYP27B1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL9835425 | 0.76 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9835295 | 0.74 | CYP3A4 (0.42) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9852718 | 0.74 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9835078 | 0.73 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9836134 | 0.73 | CYP3A4 (0.39) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL10875337 | 0.73 | OGG1 (0.56) | OGG1CYP27B1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL10364012 | 0.72 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5911584 | 0.72 | OGG1 (0.50) | OGG1CYP27B1CYP3A4CYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707976-A | FUNGICIDES, 2-SILYLOXYPROPYLIMIDAZOLE OR TRIAZOLE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1998-01-13 | — | — | US | claimed |
| US-5707976-A | FUNGICIDES, 2-SILYLOXYPROPYLIMIDAZOLE OR TRIAZOLE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1998-01-13 | — | — | US | disclosed |