SCHEMBL8662376

SCHEMBL8662376

[SiH3]C(c1ccccc1)(c1ccccc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
KCNN4 O15554 3/20 0.36
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
SRC P12931 1/20 0.32
KCNA5 P22460 2/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17931025 0.74 TSHR (0.39) TSHRKCNN4DPP4F2ALDH1A1
SCHEMBL544573 0.74 TSHR (0.39) TSHRKCNN4DPP4F2ALDH1A1
SCHEMBL327102 0.72 RIPK1 (0.40) TSHRDPP4F2HTR2ATAAR1
SCHEMBL11772008 0.70 KCNN4 (0.48) TSHRKCNN4DPP4F2ALDH1A1
SCHEMBL1053427 0.70 KCNA5 (0.47) KCNN4ALDH1A1CYP2D6MAPK1SRC
SCHEMBL9319014 0.70 KCNN4 (0.48) TSHRKCNN4DPP4F2ALDH1A1
SCHEMBL8755563 0.70 TSHR (0.36) TSHRKCNN4DPP4F2ALDH1A1
SCHEMBL1059023 0.70 MAPK1 (0.42) KCNN4ALDH1A1TAAR1MAPK1
SCHEMBL1059025 0.70 MAPK1 (0.42) KCNN4ALDH1A1TAAR1MAPK1
SCHEMBL5486513 0.70 TSHR (0.36) TSHRKCNN4DPP4F2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0778907-B1 AN INK COMPOSITION FOR USE IN INK JET PRINTING OF TEXTILES VIDEOJET SYSTEMS INT (US) 1998-09-23 EP claimed
EP-0757731-B1 AN INK COMPOSITION FOR USE IN INK JET PRINTING OF TEXTILES VIDEOJET SYSTEMS INT (US) 1998-09-23 EP claimed
CN-115197160-A Heterocyclic compounds 武田药品工业株式会社 2022-10-18 CN disclosed