SCHEMBL8662391

SCHEMBL8662391

CCOP(=O)(COC1CC(F)C(n2cnc3c(N)ncnc32)C1)OCC

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AHCY P23526 8/20 0.47
ADCY5 O95622 3/20 0.46
ADORA2B P29275 1/20 0.45
P2RY1 P47900 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663734 1.00 AHCY (0.47) AHCYADCY5ADORA2BP2RY1GAA
SCHEMBL15948858 0.88 ADCY5 (0.56) AHCYADCY5ADORA2BGAA
SCHEMBL8661848 0.86 P2RY1 (0.49) AHCYADCY5ADORA2BP2RY1
SCHEMBL8661786 0.85 AHCY (0.51) AHCYADORA2B
SCHEMBL8663380 0.85 AHCY (0.51) AHCYADORA2B
SCHEMBL8660803 0.84 ADCY5 (0.65) ADCY5ADORA2B
SCHEMBL8666797 0.81 HPRT1 (0.52)
SCHEMBL16349607 0.80 CHKA (0.41) AHCYADCY5ADORA2BP2RY1
SCHEMBL8661785 0.79 ADCY5 (0.64) ADCY5GAA
SCHEMBL8661134 0.79 ADCY5 (0.64) ADCY5GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744600-A VIRICIDES, ANTITUMOR AGENTS INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1998-04-28 US disclosed