Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666012 | 0.88 | LMNA (0.37) | LMNACES2CES1KMT2AALDH1A1 | |
| SCHEMBL14174510 | 0.87 | PPARG (0.37) | LMNAKMT2AALDH1A1KDM4EPPARG | |
| Ether SCHEMBL8663300 | 0.81 | LMNA (0.37) | LMNACES2CES1NAAAKMT2A | |
| Methoxymethane SCHEMBL8661498 | 0.81 | LMNA (0.41) | LMNACES2CES1NAAAKMT2A | |
| SCHEMBL452704 | 0.76 | LMNA (0.49) | LMNACES2CES1NAAAKMT2A | |
| SCHEMBL14174512 | 0.75 | LMNA (0.38) | LMNAKMT2AALDH1A1PPARGPPARA | |
| SCHEMBL390944 | 0.74 | LMNA (0.53) | LMNACES2CES1NAAAKMT2A | |
| Benzene SCHEMBL28132336 | 0.74 | LMNA (0.53) | LMNACES2CES1NAAAKMT2A | |
| SCHEMBL4929020 | 0.73 | NAAA (0.48) | LMNACES2CES1NAAAKMT2A | |
| Ether SCHEMBL7911427 | 0.73 | LMNA (0.46) | LMNACES2CES1NAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776658-A | PHOTOINITIATOR CONTAINING SILICON AND KETONE GROUP | AGFA-GEVAERT AG (DE) | 1998-07-07 | — | — | US | disclosed |