Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150261 | 0.84 | TK1 (0.45) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8663377 | 0.82 | TK1 (0.50) | TK1POLB | |
| SCHEMBL9148964 | 0.82 | TK1 (0.50) | TK1POLB | |
| SCHEMBL8662401 | 0.77 | TK1 (0.47) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL17157431 | 0.76 | TK1 (0.42) | TK1POLB | |
| SCHEMBL8660778 | 0.75 | TK1 (0.50) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL9149865 | 0.75 | TK1 (0.50) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL15752299 | 0.73 | TK1 (0.40) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL17174574 | 0.72 | TK1 (0.41) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL14827481 | 0.72 | LMNA (0.51) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369409-B1 | Carbocyclic nucleosides and nucleotides | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1995-01-04 | — | — | EP | claimed |
| EP-0369409-A1 | Carbocyclic nucleosides and nucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-05-23 | — | — | EP | claimed |
| EP-0369409-B1 | Carbocyclic nucleosides and nucleotides | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1995-01-04 | — | — | EP | disclosed |