Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657585 | 0.88 | PTGES2 (0.41) | PTGES2STAT3CA1CA2CA12 | |
| SCHEMBL8661463 | 0.88 | PTGES2 (0.39) | PTGES2STAT3CA1CA2CA12 | |
| SCHEMBL8659747 | 0.86 | PTGS2 (0.39) | PTGES2CA12CA9 | |
| SCHEMBL8658046 | 0.86 | PTGES2 (0.36) | PTGES2STAT3CA1CA2CA12 | |
| SCHEMBL8663230 | 0.86 | F10 (0.41) | PTGES2 | |
| SCHEMBL8659814 | 0.83 | PTGES2 (0.48) | PTGES2STAT3 | |
| SCHEMBL8770175 | 0.82 | SCN9A (0.42) | PTGES2STAT3CA1CA2CA12 | |
| SCHEMBL8663428 | 0.82 | CA2 (0.39) | PTGES2LRRK2CA2 | |
| SCHEMBL8661183 | 0.80 | CA2 (0.39) | PTGES2CA2 | |
| SCHEMBL8770171 | 0.80 | SCN9A (0.45) | PTGES2STAT3CA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |