Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666860 | 1.00 | FFAR1 (0.39) | FFAR1CA2CA1ACHESLC8A1 | |
| SCHEMBL27851553 | 0.84 | PTGS2 (0.38) | SLC8A1 | |
| SCHEMBL8845151 | 0.82 | TP53 (0.36) | SLC8A1 | |
| SCHEMBL8903397 | 0.82 | POLB (0.41) | SLC8A1 | |
| SCHEMBL8909995 | 0.82 | SLC8A1 (0.35) | SLC8A1 | |
| SCHEMBL6980329 | 0.74 | STS (0.35) | — | |
| SCHEMBL6495993 | 0.71 | CA2 (0.48) | FFAR1CA2CA1ACHECA5A | |
| SCHEMBL2968481 | 0.69 | ESR1 (0.72) | FFAR1ABCB11 | |
| SCHEMBL27221220 | 0.69 | CYP19A1 (0.58) | FFAR1SLC8A1 | |
| SCHEMBL22882748 | 0.68 | FFAR1 (0.49) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756521-A | Chroman-2-ylmethylamino derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |