Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660960 | 0.90 | MCOLN3 (0.57) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661264 | 0.87 | STAT3 (0.45) | MCOLN3ALDH1A1L3MBTL1STAT3CYP2C19 | |
| SCHEMBL8660172 | 0.86 | STAT3 (0.57) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8659594 | 0.85 | MCOLN3 (0.48) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8659806 | 0.84 | STAT3 (0.56) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8663401 | 0.84 | ALDH1A1 (0.74) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8660165 | 0.84 | STAT3 (0.57) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8661197 | 0.83 | STAT3 (0.62) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8657035 | 0.82 | PGAM1 (0.53) | MCOLN3LMNACA12CA2CA9 | |
| SCHEMBL8662978 | 0.82 | HPGD (0.46) | LMNAALDH1A1CYP2C19MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |