Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.57 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660172 | 0.90 | STAT3 (0.57) | STAT3ALOX5APFEN1PGAM1MCOLN3 | |
| SCHEMBL8663461 | 0.89 | PGAM1 (0.48) | STAT3ALOX5APFEN1PGAM1SLC22A12 | |
| SCHEMBL8660960 | 0.86 | MCOLN3 (0.57) | STAT3ALOX5APFEN1MCOLN3CA12 | |
| SCHEMBL8657035 | 0.86 | PGAM1 (0.53) | STAT3ALOX5APFEN1PGAM1MCOLN3 | |
| SCHEMBL8658522 | 0.85 | STAT3 (0.74) | STAT3ALOX5APFEN1MCOLN3CA12 | |
| SCHEMBL8662913 | 0.84 | MCOLN3 (0.54) | STAT3ALOX5APFEN1MCOLN3CA12 | |
| SCHEMBL8659594 | 0.84 | MCOLN3 (0.48) | STAT3ALOX5APFEN1PGAM1MCOLN3 | |
| SCHEMBL8658490 | 0.82 | HPGD (0.46) | STAT3PGAM1LMNASLC22A12ALDH1A1 | |
| SCHEMBL8661154 | 0.82 | STAT3 (0.53) | STAT3ALOX5APFEN1MCOLN3CA12 | |
| SCHEMBL8663418 | 0.82 | STAT3 (0.59) | STAT3ALOX5APFEN1MCOLN3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |