Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661719 | 0.91 | PTGS2 (0.41) | PTGS2PTGS1FABP4POLBMAPT | |
| SCHEMBL8659713 | 0.88 | PTGS2 (0.47) | PTGS2PTGS1FABP4F10ALOX5AP | |
| SCHEMBL8659133 | 0.87 | FABP4 (0.45) | PTGS2PTGS1FABP4F10SCN9A | |
| SCHEMBL8656123 | 0.87 | F10 (0.39) | PTGS2PTGS1POLBMAPTNPSR1 | |
| SCHEMBL8658302 | 0.86 | PTGS2 (0.39) | PTGS2PTGS1FABP4F10SCN9A | |
| SCHEMBL8659097 | 0.86 | PTGS2 (0.44) | PTGS2PTGS1POLBMAPTNPSR1 | |
| SCHEMBL8658491 | 0.86 | PTGS2 (0.47) | PTGS2PTGS1FABP4F10SCN9A | |
| SCHEMBL8659269 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1POLBMAPTNPSR1 | |
| SCHEMBL8661266 | 0.85 | PTGS2 (0.49) | PTGS2PTGS1SCN9AALOX5APFEN1 | |
| SCHEMBL8662914 | 0.85 | ALOX5AP (0.41) | PTGS2PTGS1F10SCN9AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |