Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661927 | 0.88 | PTGS2 (0.36) | PTGS2PTGS1P2RX3SCN9AF10 | |
| SCHEMBL8660177 | 0.87 | PTGS2 (0.47) | PTGS2PTGS1P2RX3F10BRD4 | |
| SCHEMBL8656219 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1F10 | |
| SCHEMBL8662979 | 0.86 | PTGS2 (0.41) | PTGS2PTGS1SCN9AF10FABP4 | |
| SCHEMBL8661281 | 0.86 | PTGS2 (0.52) | PTGS2PTGS1F10PGRAR | |
| SCHEMBL8659810 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1P2RX3SCN9AF10 | |
| SCHEMBL8662796 | 0.85 | POLB (0.41) | PTGS2PTGS1P2RX3SCN9AF10 | |
| SCHEMBL8659713 | 0.85 | PTGS2 (0.47) | PTGS2PTGS1F10FABP4 | |
| SCHEMBL6725882 | 0.85 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8659133 | 0.84 | FABP4 (0.45) | PTGS2PTGS1SCN9AF10FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |