Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | F10 | P00742 | 9/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31331765 | 0.93 | SCN9A (0.58) | SCN9AABL1ABCB1BCRF10 | |
| SCHEMBL4662973 | 0.93 | SCN9A (0.58) | SCN9AABL1ABCB1BCRF10 | |
| SCHEMBL8660189 | 0.86 | ABL1 (0.56) | SCN9AABL1ABCB1BCRF10 | |
| SCHEMBL8657061 | 0.86 | PTGS2 (0.50) | SCN9AABL1ABCB1BCRF10 | |
| SCHEMBL6728058 | 0.83 | PTGS2 (0.62) | ABL1ABCB1BCRPTGS2PTGS1 | |
| SCHEMBL8657999 | 0.83 | PTGES2 (0.56) | F10PTGS2HDAC4HDAC8PTGES2 | |
| SCHEMBL8659816 | 0.81 | CA2 (0.50) | SCN9AF10PTGS2PTGES2PTGS1 | |
| SCHEMBL6536433 | 0.81 | HDAC4 (0.56) | SCN9AF10F2NPC1TP53 | |
| SCHEMBL8659843 | 0.81 | CA2 (0.48) | SCN9APTGS2PTGES2PTGS1 | |
| SCHEMBL8632216 | 0.81 | SCN9A (0.46) | SCN9AF10F2NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | claimed |