Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 6/20 | 0.51 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659814 | 0.87 | PTGES2 (0.48) | PTGES2F10 | |
| SCHEMBL2567683 | 0.85 | KIF11 (0.56) | PTGES2KIF11TRPV1POLBF10 | |
| SCHEMBL8663230 | 0.82 | F10 (0.41) | PTGES2KIF11F10 | |
| SCHEMBL8657585 | 0.82 | PTGES2 (0.41) | PTGES2KIF11 | |
| SCHEMBL8659835 | 0.82 | KIF11 (0.53) | PTGES2KIF11TRPV1POLB | |
| SCHEMBL8770175 | 0.81 | SCN9A (0.42) | PTGES2 | |
| SCHEMBL8770171 | 0.81 | SCN9A (0.45) | PTGES2 | |
| SCHEMBL8025260 | 0.81 | KIF11 (0.65) | KIF11BACE1POLB | |
| SCHEMBL8661463 | 0.80 | PTGES2 (0.39) | PTGES2 | |
| SCHEMBL8657029 | 0.79 | KIF11 (0.46) | PTGES2KIF11TRPV1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |