SCHEMBL8663097

SCHEMBL8663097

Cc1cc(NC(=O)NC(=O)c2ccccc2Cl)c(C)c(Cl)c1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.55
PYGL P06737 12/20 0.52
PNLIP P16233 2/20 0.46
NPSR1 Q6W5P4 1/20 0.45
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10787570 0.94 GCGR (0.53) GCGRPYGLPNLIPNPC1POLB
SCHEMBL9137470 0.94 GCGR (0.56) GCGRPYGLPNLIPNPSR1
SCHEMBL8663069 0.93 GCGR (0.56) GCGRPYGLPNLIPNPSR1NPC1
SCHEMBL8661087 0.92 PYGL (0.49) GCGRPYGLNPC1POLBPKM
SCHEMBL8664412 0.92 GCGR (0.55) GCGRPYGLPNLIPNPSR1NPC1
SCHEMBL9135160 0.91 PYGL (0.49) GCGRPYGLPNLIPNPC1POLB
SCHEMBL10495917 0.91 PNLIP (0.48) GCGRPYGLPNLIPNPSR1NPC1
SCHEMBL8659805 0.91 PNLIP (0.48) GCGRPYGLPNLIPNPSR1NPC1
SCHEMBL8658907 0.90 PYGL (0.50) GCGRPYGLPNLIPNPC1POLB
SCHEMBL8661572 0.90 PYGL (0.51) GCGRPYGLPNLIPNPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4880838-A INSECTICIDES RHONE-POULENC (NL) 1989-11-14 US claimed
EP-0215841-B1 PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION RHONE-POULENC NEDERLAND B.V. (NL) 1988-11-17 EP claimed
EP-0215841-A1 PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION. UNION CARBIDE CORP (US) 1987-04-01 EP claimed
WO-1986005780-A1 PESTICIDAL 1-(4-PHENOXYPHENYL)-3-BENZOYL UREA COMPOUNDS AND PROCESS FOR PREPARATION UNION CARBIDE CORPORATION (US) 1986-10-09 WO claimed
US-5776981-A Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals NOVARTIS CORPORATION (US) 1998-07-07 US disclosed
US-5776982-A Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals NOVARTIS CORPORATION (US) 1998-07-07 US disclosed
US-5420163-A Insecticides or miticides CIBA-GEIGY (US) 1995-05-30 US disclosed
US-5135953-A Oral or injections; cattle, swine, poultry CIBA-GEIGY (US) 1992-08-04 US disclosed
EP-0211004-A1 USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS RHONE-POULENC NEDERLAND B.V. (NL) 1987-02-25 EP disclosed
WO-1986003941-A1 USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS UNION CARBIDE CORPORATION (US) 1986-07-17 WO disclosed