Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.55 |
| ▸ | PYGL | P06737 | 12/20 | 0.52 |
| ▸ | PNLIP | P16233 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663069 | 0.93 | GCGR (0.56) | GCGRPYGLPNLIPNPC1POLB | |
| SCHEMBL8663097 | 0.92 | GCGR (0.55) | GCGRPYGLPNLIPNPC1POLB | |
| SCHEMBL9135959 | 0.91 | PNLIP (0.48) | GCGRPYGLPNLIPNPC1RAB9A | |
| SCHEMBL9720333 | 0.89 | NPSR1 (0.43) | GCGRPYGLPNLIPALDH1A1NPSR1 | |
| SCHEMBL9137470 | 0.86 | GCGR (0.56) | GCGRPYGLPNLIPNPSR1 | |
| SCHEMBL10787570 | 0.86 | GCGR (0.53) | GCGRPYGLPNLIPNPC1POLB | |
| SCHEMBL8657049 | 0.85 | GCGR (0.59) | GCGRPYGLPNLIPNPC1POLB | |
| SCHEMBL8658801 | 0.85 | PYGL (0.49) | GCGRPYGLNPC1POLBPKM | |
| SCHEMBL8660804 | 0.84 | GCGR (0.52) | GCGRPYGLPNLIPALDH1A1NPSR1 | |
| SCHEMBL8658874 | 0.84 | MEN1 (0.51) | GCGRPYGLPNLIPNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |