Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 11/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786777 | 0.83 | ADRB2 (0.43) | FFAR2ADRB2TYRBRD4HSD17B10 | |
| SCHEMBL10681087 | 0.78 | ADRB2 (0.46) | FFAR2ADRB2BRD4TSHRMAPK1 | |
| SCHEMBL9979942 | 0.78 | CYP1A2 (0.39) | TYR | |
| SCHEMBL9714564 | 0.78 | ESR1 (0.50) | TYRHIF1ATDP1LMNA | |
| SCHEMBL11815736 | 0.77 | ADRB2 (0.50) | FFAR2ADRB2TYRBRD4HSD17B10 | |
| SCHEMBL3503957 | 0.77 | CYP2D6 (0.41) | HIF1AAOC3LMNA | |
| SCHEMBL96817 | 0.77 | ADRB2 (0.50) | FFAR2ADRB2TYRBRD4HSD17B10 | |
| SCHEMBL9862700 | 0.75 | ALDH1A1 (0.47) | TSHRMAPK1TDP1AOC3 | |
| SCHEMBL9006590 | 0.75 | TSHR (0.50) | TYRHSD17B10TSHRHIF1ALMNA | |
| SCHEMBL9756547 | 0.74 | SLC6A2 (0.43) | FFAR2ADRB2BRD4TDP1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072037-A | Aldol condensation, hydrogenation, dehydration, hydroformylati on, oxidation; purity, by-product inhibition, pollution contro l | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | claimed |
| EP-0069761-B1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES | FMC Corporation (US) | 1985-08-14 | — | — | EP | claimed |
| EP-0069761-A4 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. | FMC CORP (US) | 1983-05-16 | — | — | EP | claimed |
| EP-0069761-A1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES. | FMC CORP (US) | 1983-01-19 | — | — | EP | claimed |
| WO-1982002321-A1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES | FMC CORP (US) | 1982-07-22 | — | — | WO | claimed |
| US-4333950-A | MITICIDES | FMC CORPORATION (US) | 1982-06-08 | — | — | US | claimed |
| US-4263319-A | CYCLOPROPYL ESTERS | FMC CORPORATION (US) | 1981-04-21 | — | — | US | claimed |
| CN-103553992-A | One group of 2-p-chlorphenyl-3-methylbutyryl compounds | UNIV QINGDAO AGRICULTURAL | 2014-02-05 | — | — | CN | disclosed |
| CN-103553992-A | One group of 2-p-chlorphenyl-3-methylbutyryl compounds | UNIV QINGDAO AGRICULTURAL | 2014-02-05 | — | — | CN | disclosed |
| CN-1041823-C | Synthesis of N,N-diethylaminoethyl-4-chloro-alpha-isopropyl-benzyl carboxylate hydrochloride as plant growing regulating agent | UNIV WUHAN (CN) | 1999-01-27 | — | — | CN | disclosed |
| CN-1205610-A | Compounds for controlling trialeurodes vaporariorum | BRITISH TECH GROUP LTD (GB) | 1999-01-20 | — | — | CN | disclosed |
| EP-0876099-A1 | COMPOUNDS FOR CONTROL OF WHITEFLY | BTG INTERNATIONAL LIMITED (GB) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997016067-A1 | COMPOUNDS FOR CONTROL OF WHITEFLY | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-05-09 | — | — | WO | disclosed |
| US-5072037-A | Aldol condensation, hydrogenation, dehydration, hydroformylati on, oxidation; purity, by-product inhibition, pollution contro l | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| EP-0436860-A1 | Process for the preparation of 2-(4-chlorophenyl)-3-methyl-butanoic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-17 | — | — | EP | disclosed |