Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770191 | 0.83 | ALDH1A1 (0.36) | SLC6A2SLC6A4SLC6A3AOC3BCHE | |
| SCHEMBL27741965 | 0.82 | L3MBTL1 (0.44) | FFAR1LMNASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8663245 | 0.74 | FFAR2 (0.47) | AOC3ADRB2LMNABRD4FFAR2 | |
| SCHEMBL30636605 | 0.73 | ADRB2 (0.47) | SLC6A2SLC6A4SLC6A3FFAR1AOC3 | |
| SCHEMBL6158575 | 0.71 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3FFAR1AOC3 | |
| SCHEMBL8786777 | 0.71 | ADRB2 (0.43) | ALOX15ADRB2LMNASMN1; SMN2BRD4 | |
| SCHEMBL18722667 | 0.70 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3FFAR1AOC3 | |
| SCHEMBL4094943 | 0.69 | FFAR1 (0.47) | SLC6A2SLC6A4SLC6A3FFAR1AOC3 | |
| SCHEMBL16993614 | 0.69 | FFAR1 (0.50) | SLC6A2SLC6A4SLC6A3FFAR1AOC3 | |
| SCHEMBL23580752 | 0.68 | ADRB2 (0.40) | SLC6A2SLC6A4SLC6A3AOC3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009016-A2 | HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES | MERCK PATENT GMBH (DE) | 1991-06-27 | — | — | WO | disclosed |
| WO-1991009016-A1 | HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-06-27 | — | — | WO | disclosed |