Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663363 | 0.86 | MAPT (0.51) | TP53MAPTLMNAPOLBKMT2A | |
| SCHEMBL8666469 | 0.84 | MAPT (0.44) | TP53MAPTGAALMNAPOLB | |
| SCHEMBL8462423 | 0.80 | MAPT (0.47) | TP53MAPTLMNAKMT2AGPR119 | |
| SCHEMBL8468356 | 0.78 | MAPT (0.40) | TP53MAPTGAALMNAKMT2A | |
| SCHEMBL8662409 | 0.77 | MAPT (0.54) | TP53MAPTNAMPTLMNAKMT2A | |
| SCHEMBL8662814 | 0.76 | BCL2 (0.50) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL7351054 | 0.75 | SMN1; SMN2 (0.50) | MAPTGAALMNAPOLBKMT2A | |
| SCHEMBL8040438 | 0.75 | NAMPT (0.54) | TP53MAPTGAANAMPTLMNA | |
| SCHEMBL2359272 | 0.74 | NAMPT (0.55) | TP53MAPTNAMPTPOLBKMT2A | |
| SCHEMBL8986417 | 0.74 | NAMPT (0.65) | MAPTNAMPTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |