Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659193 | 0.90 | HPGD (0.48) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8661260 | 0.90 | HPGD (0.48) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8659268 | 0.90 | TSHR (0.48) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8659417 | 0.90 | HPGD (0.48) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8661797 | 0.89 | HPGD (0.52) | HPGDGFERKDM4EALDH1A1LMNA | |
| SCHEMBL8663411 | 0.88 | HPGD (0.57) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8657974 | 0.88 | PTGS2 (0.55) | HPGDSTAT3KDM4EALDH1A1LMNA | |
| SCHEMBL8659710 | 0.88 | KIF11 (0.46) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8658490 | 0.88 | HPGD (0.46) | HPGDSTAT3GFERKDM4EALDH1A1 | |
| SCHEMBL8662984 | 0.87 | HPGD (0.50) | HPGDSTAT3GFERKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | claimed |
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |