Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8443681 | 0.81 | MEN1 (0.59) | ALDH1A1SMN1; SMN2HSD17B10MAPTKMT2A | |
| SCHEMBL4332381 | 0.77 | EPHX2 (0.48) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8658916 | 0.75 | DAO (0.40) | ALDH1A1SMN1; SMN2HSD17B10HTTCYP2C19 | |
| SCHEMBL5144954 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8665315 | 0.71 | MAPT (0.37) | ALDH1A1NPC1RAB9AMAPTKMT2A | |
| SCHEMBL8667805 | 0.70 | CYP1A2 (0.53) | ALDH1A1HPGDSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8658341 | 0.70 | DAO (0.44) | ALDH1A1HPGDHSD17B10MAPTKMT2A | |
| SCHEMBL8661737 | 0.67 | EPHX2 (0.43) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2585841 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13315850 | 0.66 | HPGD (0.60) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767140-A | USEFUL FOR TREATING AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1998-06-16 | — | — | US | disclosed |