Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638822 | 0.86 | LMNA (0.40) | LMNAALDH1A1CA2CYP2C19HIF1A | |
| SCHEMBL14700212 | 0.82 | PTPN1 (0.37) | ALDH1A1CA2HPGD | |
| SCHEMBL18608295 | 0.82 | PTPN1 (0.37) | ALDH1A1CA2HPGD | |
| SCHEMBL12214451 | 0.80 | MMP2 (0.41) | LMNAALDH1A1CA2CYP2C19HIF1A | |
| SCHEMBL10296844 | 0.79 | LMNA (0.38) | LMNAALDH1A1CA2CYP2C19HIF1A | |
| SCHEMBL10055927 | 0.79 | — | — | |
| SCHEMBL9735094 | 0.79 | LMNA (0.38) | LMNAALDH1A1CA2CYP2C19HIF1A | |
| SCHEMBL10296842 | 0.79 | LMNA (0.38) | LMNAALDH1A1CA2CYP2C19HIF1A | |
| SCHEMBL10056070 | 0.79 | — | — | |
| SCHEMBL1315186 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877628-A2 | BUFFER SYSTEMS FOR USE IN STABILIZING PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997028104-A2 | BUFFER SYSTEMS FOR USE IN STABILIZING PHARMACEUTICAL PREPARATIONS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | disclosed |