Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10296844 | 0.87 | LMNA (0.38) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL10296842 | 0.87 | LMNA (0.38) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL9735094 | 0.87 | LMNA (0.38) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL2414889 | 0.86 | LMNA (0.39) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL8663853 | 0.86 | LMNA (0.33) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL619494 | 0.83 | ALDH1A1 (0.44) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL8446515 | 0.83 | ASAH1 (0.35) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL12214451 | 0.83 | MMP2 (0.41) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL12533037 | 0.83 | LMNA (0.35) | LMNAALDH1A1EGFRSRCCYP2C19 | |
| SCHEMBL12214348 | 0.83 | NAAA (0.39) | LMNAALDH1A1EGFRSRCCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368031-B | Innovative preparation and crystal of iomesol | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |