Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | XIAP | P98170 | 1/20 | 0.54 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834508 | 0.83 | LTA4H (0.38) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL18261157 | 0.80 | SLC7A5 (0.61) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL3192649 | 0.80 | CYP1A2 (0.42) | SLC15A1LTA4HSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6581938 | 0.80 | LARS1 (0.47) | SLC7A5LTA4HLAP3ANPEP | |
| SCHEMBL16669850 | 0.78 | ALPI (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL16669849 | 0.78 | ALPI (0.58) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL18342512 | 0.77 | ALDH1A1 (0.38) | — | |
| SCHEMBL30959049 | 0.75 | ALPI (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL1764633 | 0.75 | ALPI (0.63) | SLC7A5ALPIPKMPTGS1XIAP | |
| SCHEMBL26954884 | 0.75 | ALPI (0.63) | SLC7A5ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776780-A | AUTOMATIC ANALYZING; COLORIMETRIC PHOTOMETRY | CHIMERA RESEARCH & CHEMICAL, INC. (US) | 1998-07-07 | — | — | US | claimed |
| EP-0623146-A1 | COMPOUNDS AND METHODS FOR INHIBITING $g(b)-PROTEIN FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993015112-A2 | COMPOUNDS AND METHODS FOR INHIBITING β-PROTEIN FUNCTION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1993-08-05 | — | — | WO | disclosed |