SCHEMBL8664046

SCHEMBL8664046

CC(=O)c1ccc(S(=O)(=O)NC(=O)Nc2ccc(Cc3ccc(NC(=O)NS(=O)(=O)c4ccc(C(C)=O)cc4)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.58
ALDH1A1 P00352 4/20 0.58
KMT2A Q03164 3/20 0.58
MEN1 O00255 2/20 0.58
ALOX12 P18054 1/20 0.58
CA1 P00915 3/20 0.57
CA2 P00918 3/20 0.57
CA9 Q16790 3/20 0.57
CA12 O43570 2/20 0.57
HRH3 Q9Y5N1 2/20 0.56
GAA P10253 2/20 0.55
TP53 P04637 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA13 Q8N1Q1 1/20 0.53
CA14 Q9ULX7 1/20 0.53
HPGD P15428 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27680 0.86 CA12 (0.72) LMNAALDH1A1KMT2AMEN1CA1
SCHEMBL8418171 0.86 ALDH1A1 (0.57) LMNAALDH1A1KMT2AMEN1CA1
SCHEMBL5184884 0.86 KMT2A (0.77) LMNAALDH1A1KMT2AMEN1ALOX12
SCHEMBL6467693 0.84 LMNA (0.64) LMNAALDH1A1CA1CA2CA9
SCHEMBL8622851 0.84 LMNA (0.73) LMNAALDH1A1KMT2AMEN1ALOX12
SCHEMBL8627835 0.84 MAPT (0.66) LMNAALDH1A1KMT2AMEN1ALOX12
SCHEMBL8662451 0.84 LMNA (0.57) LMNAALDH1A1KMT2AMEN1CA1
SCHEMBL9483252 0.83 KMT2A (0.58) LMNAALDH1A1KMT2AMEN1ALOX12
SCHEMBL8417032 0.83 EGFR (0.57) LMNAALDH1A1KMT2AMEN1CA1
SCHEMBL7774821 0.82 LMNA (0.61) LMNAALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792755-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-11-11 EP disclosed
EP-0792755-A1 Thermosensitive recording material OJI PAPER COMPANY LIMITED (JP) 1997-09-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed