Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 12/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392652 | 0.89 | GAA (0.67) | GAAMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL112411 | 0.89 | GAA (0.67) | GAAMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL109470 | 0.84 | KMT2A (0.67) | GAAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL11199799 | 0.82 | MAPT (0.68) | GAAMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL563763 | 0.81 | PKM (0.67) | GAAMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL27653716 | 0.79 | GAA (0.53) | GAAMAPTPOLBRAB9ASMN1; SMN2 | |
| Methoxymethane SCHEMBL7082256 | 0.79 | TSHR (0.61) | GAAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| Di(Hydroxyethyl)Ether SCHEMBL7078302 | 0.77 | TDP1 (0.66) | GAAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5704002 | 0.76 | GAA (0.67) | GAAMAPTPOLBRAB9ASMN1; SMN2 | |
| SCHEMBL116088 | 0.76 | GAA (0.70) | GAAMAPTPOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646108-B1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1998-10-14 | — | — | EP | claimed |