Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL7082256 | 0.94 | TSHR (0.61) | KMT2ATDP1TSHRALDH1A1PKM | |
| Di(Hydroxyethyl)Ether SCHEMBL7078302 | 0.92 | TDP1 (0.66) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL8749218 | 0.87 | KMT2A (0.62) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL126989 | 0.87 | KMT2A (0.70) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL29390514 | 0.87 | KMT2A (0.70) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL2470932 | 0.86 | KAT2B (0.52) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL8664267 | 0.84 | GAA (0.56) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL563763 | 0.84 | PKM (0.67) | KMT2ATDP1TSHRALDH1A1PKM | |
| SCHEMBL9507998 | 0.83 | MAPT (0.54) | KMT2ATSHRALDH1A1PKMMEN1 | |
| Hydrochloric Acid SCHEMBL9651443 | 0.83 | KAT2B (0.53) | KMT2ATDP1TSHRALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 873 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20070033743-A1 | direct dyes | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| CN-1903161-A | Composition for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2007-01-31 | — | — | CN | claimed |
| CN-1899244-A | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2007-01-24 | — | — | CN | claimed |
| EP-1738800-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1738801-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| US-5496377-A | HAIR DYES, NITRO-AMINE COMPOUNDS | L'OREAL (FR) | 1996-03-05 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0659399-A1 | Process of direct hair using steam | L'OREAL (FR) | 1995-06-28 | — | — | EP | claimed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| EP-0480829-B1 | Hair dyeing composition containing anthraquinones | OREAL (FR) | 1994-04-06 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-5226924-A | 1,4-DI(MONO- OR POLY) HYDROXYALKYLAMINO-9,10-ANTHRAQUINONES FOR DYEING HUMAN KERATINOUS FIBRES, COSMETIC COMPOSITION CONTAINING THEM IN COMBINATION WITH AZO AND NITROBENZENE DYES, AND HAIR-DYEING PROCESS USING THEM | L'OREAL (FR) | 1993-07-13 | — | — | US | claimed |
| EP-0480829-A1 | Hair dyeing composition containing anthraquinones | L'OREAL (FR) | 1992-04-15 | — | — | EP | claimed |
| US-4494953-A | 2,4-Dihydroxydiphenylamines and hair dyeing compositions and method | L'OREAL (FR) | 1985-01-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | KRT18, BRD7, KAT7 | KMT2A 254/4885TDP1 2418/4885TSHR 3126/4885 |
| US-20070033743-A1 | direct dyes | KRT18, DSG1, DSP | KMT2A 243/4885TDP1 1167/4885TSHR 4673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.