Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003720 | 0.84 | TSHR (0.50) | TSHRMAPK1TDP1CYP3A4LMNA | |
| SCHEMBL8160044 | 0.83 | CYP3A4 (0.43) | TSHRMAPK1TDP1CYP3A4TNF | |
| SCHEMBL9392558 | 0.80 | EPAS1 (0.40) | TNFRIPK1 | |
| SCHEMBL10748076 | 0.78 | TAAR1 (0.38) | TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL22527193 | 0.78 | AR (0.34) | TSHRTDP1TNFRIPK1HTR2A | |
| SCHEMBL9847889 | 0.78 | TNF (0.46) | TSHRMAPK1TDP1TNFRIPK1 | |
| SCHEMBL8974765 | 0.75 | CYP3A4 (0.34) | TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL6415524 | 0.74 | TSHR (0.48) | TSHRMAPK1TDP1CYP3A4LMNA | |
| SCHEMBL11048039 | 0.73 | TSHR (0.43) | TSHRMAPK1TDP1CYP3A4 | |
| SCHEMBL8156993 | 0.73 | CYP3A4 (0.60) | TSHRMAPK1TDP1CYP3A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583705-A1 | Process for the preparation of 2,3,4-trichloro-5-fluoro-benzoylchloride | BAYER AG (DE) | 1994-02-23 | — | — | EP | claimed |
| US-5723613-A | Process for the free-radical chlorination or bromination of methyl aromatic compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0537540-B1 | Process for the radical chlorination or bromination of methyl substituted aromatics | BAYER AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| EP-0537540-A1 | Process for the radical chlorination or bromination of methyl substituted aromatics | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |