Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | CTSG | P08311 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663995 | 0.74 | GPR3 (0.38) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8663948 | 0.74 | GPR3 (0.38) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8665552 | 0.74 | GPR3 (0.38) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8662797 | 0.71 | DRD2 (0.43) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8660919 | 0.70 | GPR3 (0.34) | CYP3A4ALDH1A1ALOX15CYP1A2CYP2D6 | |
| SCHEMBL8663891 | 0.70 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8665959 | 0.69 | DRD2 (0.37) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL8665291 | 0.69 | DRD2 (0.37) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL30186568 | 0.69 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL10354216 | 0.69 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1CYP3A4ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744666-A | Process for preparing an alkynyl fulvene group containing compound and said compound | PHILLIPS PETROLEUM COMPANY (US) | 1998-04-28 | — | — | US | claimed |
| US-5728908-A | Process for preparing a bridged ligand and said bridged ligand | PHILLIPS PETROLEUM COMPANY (US) | 1998-03-17 | — | — | US | claimed |
| US-5744666-A | Process for preparing an alkynyl fulvene group containing compound and said compound | PHILLIPS PETROLEUM COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| US-5728908-A | Process for preparing a bridged ligand and said bridged ligand | PHILLIPS PETROLEUM COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5631203-A | Metallocene compounds and preparation thereof containing terminal alkynes | PHILLIPS PETROLEUM COMPANY (US) | 1997-05-20 | — | — | US | disclosed |