Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.34 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665552 | 1.00 | GPR3 (0.38) | GPR3ALOX15ALDH1A1CYP3A4LYPLA1 | |
| SCHEMBL8663995 | 1.00 | GPR3 (0.38) | GPR3ALOX15ALDH1A1CYP3A4LYPLA1 | |
| SCHEMBL8660919 | 0.92 | GPR3 (0.34) | GPR3ALOX15ALDH1A1CYP3A4LYPLA1 | |
| SCHEMBL8663886 | 0.86 | NPC1 (0.33) | GPR3ALDH1A1 | |
| SCHEMBL8663252 | 0.80 | NPC1 (0.34) | ALDH1A1 | |
| SCHEMBL8664349 | 0.74 | CYSLTR2 (0.40) | ALOX15ALDH1A1CYP3A4CYSLTR2CYSLTR1 | |
| SCHEMBL25808313 | 0.73 | NPC1 (0.38) | ALDH1A1 | |
| SCHEMBL8663258 | 0.72 | ALDH1A1 (0.45) | GPR3ALOX15ALDH1A1CYP3A4 | |
| SCHEMBL8664369 | 0.72 | GPR84 (0.39) | GPR3ALOX15ALDH1A1CYP3A4CYSLTR2 | |
| SCHEMBL8661943 | 0.72 | CYP1A2 (0.39) | ALOX15ALDH1A1CYP3A4CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744666-A | Process for preparing an alkynyl fulvene group containing compound and said compound | PHILLIPS PETROLEUM COMPANY (US) | 1998-04-28 | — | — | US | claimed |
| US-5728908-A | Process for preparing a bridged ligand and said bridged ligand | PHILLIPS PETROLEUM COMPANY (US) | 1998-03-17 | — | — | US | claimed |
| US-5744666-A | Process for preparing an alkynyl fulvene group containing compound and said compound | PHILLIPS PETROLEUM COMPANY (US) | 1998-04-28 | — | — | US | disclosed |
| US-5728908-A | Process for preparing a bridged ligand and said bridged ligand | PHILLIPS PETROLEUM COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5631203-A | Metallocene compounds and preparation thereof containing terminal alkynes | PHILLIPS PETROLEUM COMPANY (US) | 1997-05-20 | — | — | US | disclosed |