Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624762 | 0.85 | KMT2A (0.49) | KMT2APAX8ALDH1A1LMNANPC1 | |
| SCHEMBL28621564 | 0.85 | GAA (0.47) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL8662612 | 0.83 | NPC1 (0.57) | KMT2AHSD11B1F2PRSS1PRSS2 | |
| SCHEMBL114044 | 0.83 | ALDH1A1 (0.57) | KMT2APAX8F2PRSS1PRSS2 | |
| SCHEMBL787249 | 0.83 | LMNA (0.54) | HSD11B1LMNACA2 | |
| SCHEMBL1282212 | 0.83 | MMP1 (0.55) | KMT2AHSD11B1CA2 | |
| SCHEMBL24334708 | 0.81 | HTT (0.60) | KMT2AF2PRSS1PRSS2PRSS3 | |
| SCHEMBL1283002 | 0.80 | F2 (0.48) | KMT2AHSD11B1F2PRSS1PRSS2 | |
| SCHEMBL21590247 | 0.74 | PLCG1 (0.46) | KMT2AHSD11B1F2PRSS1PRSS2 | |
| SCHEMBL20503341 | 0.73 | LMNA (0.60) | HSD11B1LMNACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365984-A | LOX inhibitors | 癌症研究协会皇家癌症医院 | 2021-09-07 | — | — | CN | disclosed |
| EP-0714889-B1 | SULFONYLSEMICARBAZIDE DERIVATIVE AND COMPOSITION FOR KEEPING CUT FLOWER FRESHNESS | MEIJI SEIKA KAISHA (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5723407-A | Sulfonylsemicarbazide derivatives and preservative composition for preserving the freshness of flower of cut flowers | MEIJI SEIKA KAISHA, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0714889-A1 | SULFONYLSEMICARBAZIDE DERIVATIVE AND COMPOSITION FOR KEEPING CUT FLOWER FRESHNESS | MEIJI SEIKA KAISHA LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |