Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 3/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6428668 | 1.00 | P2RX4 (0.33) | P2RX4P2RX1P2RX3P2RX7MEN1 | |
| SCHEMBL112009 | 0.81 | — | — | |
| SCHEMBL6738847 | 0.81 | TYR (0.39) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| Orthocresol SCHEMBL6013643 | 0.79 | HSD17B10 (0.38) | MEN1POLBKMT2AALDH1A1LMNA | |
| Pyrazine SCHEMBL7593109 | 0.74 | TYR (0.31) | — | |
| SCHEMBL6017891 | 0.72 | CES2 (0.42) | MEN1POLBKMT2AALDH1A1LMNA | |
| SCHEMBL8089087 | 0.71 | MAPK1 (0.36) | POLBALDH1A1LMNAKDM4EMAPT | |
| Propionic Acid SCHEMBL28491340 | 0.68 | FFAR3 (0.42) | ALDH1A1 | |
| SCHEMBL441607 | 0.68 | — | — | |
| SCHEMBL21380433 | 0.66 | AKT1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5711987-A | Electronic coatings | DOW CORNING CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5455876-A | High-speed external integrated optical modulator | GENERAL MICROWAVE ISRAEL CORPORATION (IL) | 1995-10-03 | — | — | US | disclosed |