Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666430 | 0.86 | SLC9A1 (0.32) | ALDH1A1LMNAKMT2ASMN1; SMN2SLC9A1 | |
| SCHEMBL8666392 | 0.84 | SLC9A1 (0.35) | SLC9A1SLC9A2THRATHRB | |
| SCHEMBL8666395 | 0.84 | SLC9A1 (0.35) | SLC9A1SLC9A2THRATHRB | |
| SCHEMBL8665023 | 0.83 | SMN1; SMN2 (0.33) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL8665020 | 0.83 | SMN1; SMN2 (0.33) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL8664961 | 0.81 | THRA (0.32) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL8664964 | 0.81 | THRA (0.32) | KMT2ASMN1; SMN2SLC9A1SLC9A2THRA | |
| SCHEMBL7798561 | 0.80 | SLC9A1 (0.57) | SLC9A1SLC9A2 | |
| SCHEMBL10386884 | 0.79 | HTT (0.40) | POLBELANEALDH1A1LMNAHPGD | |
| SCHEMBL8665308 | 0.78 | SLC9A1 (0.38) | POLBSLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731351-A | Alkenyl-benzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |