Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664961 | 1.00 | THRA (0.32) | THRATHRBGABBR2GABBR1KMT2A | |
| SCHEMBL8665020 | 0.89 | SMN1; SMN2 (0.33) | THRATHRBKMT2ASMN1; SMN2SLC9A1 | |
| SCHEMBL8665023 | 0.89 | SMN1; SMN2 (0.33) | THRATHRBKMT2ASMN1; SMN2SLC9A1 | |
| SCHEMBL8666392 | 0.85 | SLC9A1 (0.35) | THRATHRBSLC9A1SLC9A2 | |
| SCHEMBL8666395 | 0.85 | SLC9A1 (0.35) | THRATHRBSLC9A1SLC9A2 | |
| SCHEMBL7792992 | 0.82 | SLC9A1 (0.53) | SLC9A1SLC9A2 | |
| SCHEMBL7792990 | 0.82 | SLC9A1 (0.53) | SLC9A1SLC9A2 | |
| SCHEMBL8667468 | 0.82 | KMT2A (0.32) | THRATHRBKMT2ASMN1; SMN2SLC9A1 | |
| SCHEMBL8667466 | 0.82 | KMT2A (0.32) | THRATHRBKMT2ASMN1; SMN2SLC9A1 | |
| SCHEMBL8664475 | 0.81 | POLB (0.38) | THRATHRBKMT2ASMN1; SMN2SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731351-A | Alkenyl-benzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |