Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901777 | 0.89 | ALDH1A1 (0.79) | KDM4EALDH1A1MAPTDHODHKDR | |
| SCHEMBL8664992 | 0.86 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPTDHODHKDR | |
| SCHEMBL8667765 | 0.85 | ALDH1A1 (0.56) | KDM4EALDH1A1MAPTDHODHKDR | |
| SCHEMBL28442197 | 0.77 | NPC1 (0.76) | ALDH1A1MAPTGAAKMT2ARXFP1 | |
| SCHEMBL1507135 | 0.76 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTKDRGAA | |
| Hydrochloric Acid SCHEMBL28079784 | 0.75 | NPC1 (0.46) | KDM4EALDH1A1KDRGAA | |
| SCHEMBL7825161 | 0.74 | MAPT (0.68) | KDM4EALDH1A1MAPTDHODHKMT2A | |
| SCHEMBL29168828 | 0.74 | MAPT (0.65) | KDM4EALDH1A1MAPTTOP1KMT2A | |
| SCHEMBL8665346 | 0.74 | ALDH1A1 (0.54) | KDM4EALDH1A1MAPTDHODHKMT2A | |
| SCHEMBL28678450 | 0.74 | KDR (0.74) | KDM4EMAPTDHODHKDRTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843868-A | Pryidine-2,3-dicarboxylic acid diamide derivatives and herbicides comprising said derivatives as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0799825-A1 | Pyridine-2,3-dicarboxylic acid diamide derivatives and herbicides comprising said derivatives as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |