Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031422 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1SMN1; SMN2CD38MAPT | |
| SCHEMBL3548766 | 0.73 | MAPT (0.38) | KDM4EDHODHALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL7452418 | 0.69 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2NPSR1JAK2 | |
| SCHEMBL8664634 | 0.68 | KDM4E (0.62) | KDM4EDHODHALDH1A1RXFP1GAA | |
| SCHEMBL1507135 | 0.68 | ALDH1A1 (0.45) | KDM4EPAK1ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL28917190 | 0.67 | PRKCI (0.40) | KDM4EPTPN11NNMTALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28079784 | 0.67 | NPC1 (0.46) | KDM4EPAK1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14771234 | 0.67 | NPSR1 (0.42) | KDM4EPTPN11NPSR1RXFP1MAPT | |
| SCHEMBL10126900 | 0.67 | TAS1R3 (0.54) | KDM4EALDH1A1GAAMAPTPOLB | |
| SCHEMBL1719653 | 0.66 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2CD38MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843868-A | Pryidine-2,3-dicarboxylic acid diamide derivatives and herbicides comprising said derivatives as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| EP-0799825-A1 | Pyridine-2,3-dicarboxylic acid diamide derivatives and herbicides comprising said derivatives as active ingredient | NIHON NOHYAKU CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |