Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.48 |
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 7/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 7/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 7/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 7/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7394330 | 0.92 | CTSD (0.49) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL7403620 | 0.91 | CTSD (0.47) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL7396675 | 0.91 | CTSD (0.47) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL7402232 | 0.88 | CTSD (0.46) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL8605875 | 0.88 | PSEN1 (0.56) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL7400099 | 0.86 | REN (0.49) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL7454879 | 0.85 | PSEN1 (0.43) | CTSDRENPSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL8665816 | 0.84 | PSEN1 (0.42) | CTSDRENPSEN1PSEN2APH1B | |
| SCHEMBL8568989 | 0.84 | PSEN1 (0.47) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL7402349 | 0.83 | PSEN1 (0.48) | CTSDPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750648-A | HUMAN IMMUNODEFICIENCY VIRUS | G.D. SEARLE & CO. (US) | 1998-05-12 | — | — | US | disclosed |