SCHEMBL8664666

SCHEMBL8664666

CN(C)NC(=O)NS(=O)(=O)c1cscc1C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.34
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
MMP13 P45452 1/20 0.31
ATM Q13315 1/20 0.31
PPARG P37231 1/20 0.30
RAB9A P51151 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NR2E3 Q9Y5X4 1/20 0.30
NCOR2 Q9Y618 1/20 0.30
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30
CA12 O43570 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8661050 0.86 KMT2A (0.35) CA1CA2RAB9ACA9
SCHEMBL27444584 0.76 PTPN1 (0.41) PTPN1CA1CA2MMP1MMP2
SCHEMBL11102242 0.74 PTPN1 (0.36) PTPN1CA1CA2CA12CA9
SCHEMBL11099623 0.73 GAA (0.46) RAB9A
SCHEMBL11100023 0.71 GAA (0.40) PTPN1CA1CA2CA9
SCHEMBL11100017 0.71 GAA (0.55)
SCHEMBL19334383 0.70 LMNA (0.43) PTPN1CA1CA2MMP1MMP2
SCHEMBL11097648 0.68 GAA (0.37) PTPN1
SCHEMBL5069150 0.68 LMNA (0.54) CA1CA2MMP1MMP2MMP9
SCHEMBL11485151 0.68 ALDH1A1 (0.43) PTPN1CA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0714889-B1 SULFONYLSEMICARBAZIDE DERIVATIVE AND COMPOSITION FOR KEEPING CUT FLOWER FRESHNESS MEIJI SEIKA KAISHA (JP) 1998-11-25 EP claimed
US-5723407-A Sulfonylsemicarbazide derivatives and preservative composition for preserving the freshness of flower of cut flowers MEIJI SEIKA KAISHA, LTD. (JP) 1998-03-03 US claimed