Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476501 | 0.82 | CA1 (0.40) | CYP1A2CA1CA2ATMAPP | |
| SCHEMBL19334383 | 0.79 | LMNA (0.43) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL11485151 | 0.76 | ALDH1A1 (0.43) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL8664666 | 0.76 | PTPN1 (0.34) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL11557295 | 0.75 | PTPN1 (0.40) | PTPN1CYP1A2CA1CA2MMP1 | |
| SCHEMBL10835741 | 0.75 | CA2 (0.48) | PTPN1CYP1A2CA1CA2CA12 | |
| Hydrochloric Acid SCHEMBL11486084 | 0.73 | PTPN1 (0.39) | PTPN1CA1CA2MMP1MMP2 | |
| SCHEMBL4433906 | 0.72 | CA1 (0.70) | CYP1A2MAPTCA1CA2MMP1 | |
| SCHEMBL11102242 | 0.71 | PTPN1 (0.36) | PTPN1MAPTCA1CA2CA12 | |
| SCHEMBL11482624 | 0.70 | FTO (0.33) | CYP1A2ALDH1A1LMNATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137119-C | Substituted thineyl (amino) sulfonylureas | — | 2004-02-04 | — | — | CN | disclosed |
| CN-1368971-A | Substituted thineyl (amino) sulfonylureas | BAYER AG (DE) | 2002-09-11 | — | — | CN | disclosed |