SCHEMBL8664686

SCHEMBL8664686

CN(C)C(=S)OCn1c(Br)c(Br)c(S(=O)(=O)C(F)(F)F)c1-c1ccc(Cl)cc1.NC(O)=S

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8664683 0.81 ALDH1A1 (0.32) MEN1KMT2A
SCHEMBL8665381 0.79 EPAS1 (0.35) PTGS1PTGS2MEN1KMT2A
SCHEMBL8663775 0.76 EPAS1 (0.32) PTGS1PTGS2MEN1KMT2A
SCHEMBL8664049 0.73 MEN1 (0.38) PTGS1PTGS2MEN1KMT2A
SCHEMBL8666764 0.71 PTGS2 (0.41) PTGS1PTGS2MEN1KMT2A
SCHEMBL8666760 0.69 EPAS1 (0.33) PTGS1PTGS2
SCHEMBL8986682 0.61 MEN1 (0.36) MEN1KMT2A
SCHEMBL8986693 0.61 MEN1 (0.38) MEN1KMT2A
SCHEMBL7784780 0.60 PTGS1 (0.37) PTGS1PTGS2MEN1KMT2A
SCHEMBL1180312 0.59 PTGS2 (0.35) PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5739155-A Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID CO. (US) 1998-04-14 US disclosed
US-5484807-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents BASF AKTIENGESELLSCHAFT 1996-01-16 US disclosed
US-5468877-A FOR PROTECTING CROPS AMERICAN CYANAMID COMPANY (US) 1995-11-21 US disclosed