Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627436 | 0.84 | TSHR (0.45) | TSHRGABRA1GABRB2HPGDAKR1B1 | |
| SCHEMBL6773227 | 0.81 | TSHR (0.57) | TSHRGABRA1GABRB2HPGDAKR1B1 | |
| SCHEMBL30483161 | 0.81 | TSHR (0.57) | TSHRGABRA1GABRB2HPGDAKR1B1 | |
| SCHEMBL4071095 | 0.81 | TSHR (0.57) | TSHRGABRA1GABRB2HPGDAKR1B1 | |
| SCHEMBL28179845 | 0.79 | TSHR (0.41) | TSHRGABRA1GABRB2HPGDAKR1B1 | |
| SCHEMBL21632329 | 0.79 | MEN1 (0.50) | TSHRCYP1A2GABBR2GABBR1ALDH1A1 | |
| SCHEMBL3383530 | 0.79 | ROCK2 (0.49) | TSHRHPGDCYP1A2GABBR2GABBR1 | |
| SCHEMBL3385715 | 0.79 | ROCK2 (0.49) | TSHRCYP1A2GABBR2GABBR1ALDH1A1 | |
| SCHEMBL8425190 | 0.78 | ALDH1A1 (0.38) | TSHRGABRA1GABRB2CYP1A2GABBR2 | |
| SCHEMBL8015528 | 0.78 | TSHR (0.48) | TSHRGABRA1GABRB2HPGDAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760251-A | Taxol process and compounds | SEPRACOR, INC. (US) | 1998-06-02 | — | — | US | disclosed |