SCHEMBL8664741

SCHEMBL8664741

CCOc1ccc(Oc2ccncn2)c(SC)c1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.39
BRAF P15056 1/20 0.32
KDR P35968 1/20 0.32
MAPK14 Q16539 1/20 0.32
TNNI3K Q59H18 1/20 0.32
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8672951 0.85 KMT2A (0.34) BRAFKDRMAPK14TNNI3K
SCHEMBL8667379 0.85 BRAF (0.33) BRAFKDRMAPK14TNNI3K
SCHEMBL8669996 0.84 L3MBTL1 (0.33) BRAFKDRMAPK14TNNI3K
SCHEMBL8665290 0.79 HPGD (0.38) HPGDBRAFKDRMAPK14TNNI3K
SCHEMBL8668430 0.76 BRAF (0.38) HPGDBRAFKDRMAPK14TNNI3K
SCHEMBL8667134 0.70 PPARG (0.34) HPGDBRAFKDRMAPK14TNNI3K
SCHEMBL18374891 0.68 CYP1A2 (0.44) HPGDMAPK1
SCHEMBL8669895 0.68 BRAF (0.33) BRAFKDRMAPK14TNNI3K
SCHEMBL1416291 0.67
SCHEMBL8668648 0.66 KDR (0.34) BRAFKDRMAPK14TNNI3K

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5723412-A HERBICIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed