Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667379 | 0.83 | BRAF (0.33) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8672951 | 0.78 | KMT2A (0.34) | BRAFKDRMAPK14TNNI3KKMT2A | |
| SCHEMBL8669996 | 0.77 | L3MBTL1 (0.33) | BRAFKDRMAPK14TNNI3K | |
| SCHEMBL8669834 | 0.77 | BRAF (0.39) | BRAFKDRMAPK14TNNI3KTSHR | |
| SCHEMBL8664741 | 0.76 | HPGD (0.39) | BRAFKDRMAPK14TNNI3KHPGD | |
| SCHEMBL21376359 | 0.69 | PARP1 (0.39) | SMN1; SMN2ALDH1A1POLBHSD17B10PARP1 | |
| SCHEMBL30874294 | 0.68 | GRK3 (0.33) | SLC6A4PARP1 | |
| SCHEMBL28769171 | 0.68 | GRK3 (0.33) | SLC6A4PARP1 | |
| SCHEMBL9007828 | 0.67 | SMN1; SMN2 (0.56) | MAPK14TSHRSMN1; SMN2HPGDMRGPRX1 | |
| SCHEMBL8665228 | 0.66 | BRAF (0.34) | BRAFKDRMAPK14TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723412-A | HERBICIDES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-03-03 | — | — | US | disclosed |