Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667027 | 0.88 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1EGFRTDP2PAX8 | |
| SCHEMBL8665999 | 0.86 | MAPT (0.52) | HSP90AA1HSP90AB1EGFRTDP2PAX8 | |
| SCHEMBL8102262 | 0.86 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1FGFR1SRCFGFR2 | |
| SCHEMBL8092553 | 0.85 | TDP2 (0.61) | HSP90AA1HSP90AB1EGFRTDP2PAX8 | |
| SCHEMBL8665166 | 0.84 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1TDP2PAX8HKDC1 | |
| SCHEMBL8102104 | 0.83 | TDP2 (0.52) | HSP90AA1HSP90AB1EGFRTDP2PAX8 | |
| SCHEMBL8106236 | 0.79 | FGFR1 (0.50) | HSP90AA1HSP90AB1TDP2PAX8HKDC1 | |
| SCHEMBL8100343 | 0.74 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1TDP2PAX8HKDC1 | |
| SCHEMBL8102495 | 0.73 | TDP2 (0.46) | HSP90AA1HSP90AB1TDP2PAX8HKDC1 | |
| SCHEMBL8102319 | 0.73 | TDP2 (0.68) | HSP90AA1HSP90AB1TDP2PAX8HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882706-A1 | Cell adhesion inhibitors | ELI LILLY AND COMPANY (US) | 1998-12-09 | — | — | EP | disclosed |