Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977572 | 0.81 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL20805929 | 0.79 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1944726 | 0.78 | TSHR (0.50) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL16060 | 0.76 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL17267140 | 0.75 | — | — | |
| SCHEMBL14901 | 0.75 | — | — | |
| SCHEMBL9889643 | 0.74 | ALDH1A1 (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL8632003 | 0.74 | TSHR (0.56) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1548741 | 0.74 | — | — | |
| SCHEMBL17047583 | 0.74 | TSHR (0.62) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192817-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-5726267-A | POLYETHER-ACRYLIC AMIDE COPOLYMERS, BINDERS FOR CERAMICS, LOW VISCOSITY | NALCO CHEMICAL COMPANY (US) | 1998-03-10 | — | — | US | disclosed |